After years of trying, biologists have succeeded in creating an extremely bright red fluorescent protein in the lab. This is good news for researchers, including cancer and stem cell researchers, who use fluorescent proteins to track essential cellular processes. The …
Research highlight: Bright red fluorescent protein created Read more »
The small GTPase RhoA is best known for its ability to remodel the actin cytoskeleton of cells. To study the mechanism underlying the spatiotemporal control of RhoA activity by GEFs, single cell imaging was performed with an improved FRET sensor reporting on the nucleotide loading …
Research highlight: Subcellular location of signaling proteins determines cell shape Read more »
During the 15th dies natalis celebration of the FNWI the first edition of the Amsterdam Science Magazine was presented to the dean. Edited by Renee van Amerongen, among others, this first issue features work from the section of Molecular Cytology. …
Official launch of the Amsterdam Science Magazine Read more »
17 February 2015 Giulia De Luca, PhD candidate with the Molecular Cytology group at the Swammerdam Institute of Life Sciences (SILS), won the Upcoming Scientist Award at the Innovation for Health conference held in Amsterdam in February. At the conference …
Giulia De Luca (SILS) wins Upcoming Scientist Award at Innovation for Health 2015 Read more »
Renée van Amerongen has been awarded a highly competitive VIDI grant (EUR 800K) by the national research council NWO! This grant will allow Renée to expand her research team to investigate the molecular mechanisms that control stem cell activity. For …
Giulia De Luca wins Amsterdam Science & Innovation Award 2014 11 June 2014 Giulia De Luca’s Re-scan Confocal Microscopy (RCM) method won the 2014 edition of the Amsterdam Science & Innovation Award, an annual award in recognition of innovative ideas …
Rescan Confocal Microscopy: Winner of Amsterdam Science & Innovation Award 2014 Read more »
The quality of super resolution images obtained by stochastic single-molecule microscopy critically depends on image analysis algorithms. We find that the choice of background estimator is often the most important determinant of reconstruction quality. A variety of techniques have found …
Research highlight: Taming the image background beast Read more »
Annexins, found in most eukaryotic species, are cytosolic proteins that are able to bind negatively-charged phospholipids in a calcium-dependent manner. Annexin A4 (AnxA4) has been implicated in diverse cellular processes, including the regulation of exocytosis and ion-transport; however, its precise …